During his lecture at the Strelka Institute of Media, Architecture and Design, Alexandre D' Hooghe shared his foresight with regards to street signage. He thinks that there will soon be no need for street signs since the information would be getting directly into your phone or other device. This will obviously dramatically change the urban landscape.
It remains to be seen whether this prediction comes true or not. While it may be plausible that new towns will not have street signage, there is little reason to believe present street signs are going to be removed.
Lecture at Strelka Institute on 28 Jan 2013